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PSA Regulates Androgen Receptor Expression In Prostate Cancer Cells

BACKGROUND: Prostate Specific Antigen (PSA) is a pivotal downstream target gene of the Androgen Receptor (AR), and a serum biomarker to monitor prostate cancer (PrCa) progression. It has been reported that PSA transactivates AR, but the mechanistic requirements of this response have not been investi...

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Bibliographic Details
Main Authors: Saxena, Parmita, Trerotola, Marco, Wang, Tao, Li, Jing, Sayeed, Aejaz, VanOudenhove, Jennifer, Adams, Dave S., FitzGerald, Thomas J., Altieri, Dario C., Languino, Lucia R.
Format: Artigo
Language:Inglês
Published: 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404455/
https://ncbi.nlm.nih.gov/pubmed/21956655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21482
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