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Cytokine-Conditioned Dendritic Cells Induce Humoral Tolerance to Protein Therapy in Mice
A major obstacle in the genetic therapy of inherited metabolic disease is host immune responses to the therapeutic protein. This is best exemplified by inhibitor formation in the protein therapy for hemophilia A. An approach to overcoming this is induction of immunological tolerance to the therapeut...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Mary Ann Liebert, Inc.
2012
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3404424/ https://ncbi.nlm.nih.gov/pubmed/22468961 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.225 |
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