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Cytokine-Conditioned Dendritic Cells Induce Humoral Tolerance to Protein Therapy in Mice

A major obstacle in the genetic therapy of inherited metabolic disease is host immune responses to the therapeutic protein. This is best exemplified by inhibitor formation in the protein therapy for hemophilia A. An approach to overcoming this is induction of immunological tolerance to the therapeut...

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Bibliografski detalji
Glavni autori: Sule, Gautam, Suzuki, Masataka, Guse, Kilian, Cela, Racel, Rodgers, John R., Lee, Brendan
Format: Artigo
Jezik:Inglês
Izdano: Mary Ann Liebert, Inc. 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404424/
https://ncbi.nlm.nih.gov/pubmed/22468961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hum.2011.225
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