Restoration of the serum level of SERPINF1 does not correct the bone phenotype in Serpinf1(−/−) null mice

Osteogenesis imperfecta (OI) is a group of genetic disorders characterized by bone fragility and deformity. OI type VI is unique owing to the mineralization defects observed in patient biopsies. Furthermore, it has been reported to respond less well to standard therapy with bisphosphonates (1). Othe...

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Vydáno v:Mol Genet Metab
Hlavní autoři: Rajagopal, Abbhirami, Homan, Erica P, Joeng, Kyusang, Suzuki, Masataka, Bertin, Terry, Cela, Racel, Munivez, Elda, Dawson, Brian, Jiang, Ming-Ming, Gannon, Frank, Crawford, Susan, Lee, Brendan H
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4788589/
https://ncbi.nlm.nih.gov/pubmed/26693895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2015.11.015
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