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Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain
Two polypyrimidine tract RNA-binding proteins (PTBs), one near-ubiquitously expressed (Ptbp1) and another highly tissue-restricted (Ptbp2), regulate RNA in interrelated but incompletely understood ways. Ptbp1, a splicing regulator, is replaced in the brain and differentiated neuronal cell lines by P...
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Main Authors: | , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Cold Spring Harbor Laboratory Press
2012
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3404389/ https://ncbi.nlm.nih.gov/pubmed/22802532 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.191338.112 |
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