Ptbp2 represses adult-specific splicing to regulate the generation of neuronal precursors in the embryonic brain

Two polypyrimidine tract RNA-binding proteins (PTBs), one near-ubiquitously expressed (Ptbp1) and another highly tissue-restricted (Ptbp2), regulate RNA in interrelated but incompletely understood ways. Ptbp1, a splicing regulator, is replaced in the brain and differentiated neuronal cell lines by P...

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Bibliografiske detaljer
Main Authors: Licatalosi, Donny D., Yano, Masato, Fak, John J., Mele, Aldo, Grabinski, Sarah E., Zhang, Chaolin, Darnell, Robert B.
Format: Artigo
Sprog:Inglês
Udgivet: Cold Spring Harbor Laboratory Press 2012
Fag:
Research Paper
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404389/
https://ncbi.nlm.nih.gov/pubmed/22802532
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.191338.112
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