A Src family kinase–Shp2 axis controls RUNX1 activity in megakaryocyte and T-lymphocyte differentiation

Hematopoietic development occurs in complex microenvironments and is influenced by key signaling events. Yet how these pathways communicate with master hematopoietic transcription factors to coordinate differentiation remains incompletely understood. The transcription factor RUNX1 plays essential ro...

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Autors principals: Huang, Hui, Woo, Andrew J., Waldon, Zachary, Schindler, Yocheved, Moran, Tyler B., Zhu, Helen H., Feng, Gen-Sheng, Steen, Hanno, Cantor, Alan B.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2012
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404386/
https://ncbi.nlm.nih.gov/pubmed/22759635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.192054.112
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