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Reperfusion rather than Ischemia drives the Formation of Ubiquitin Aggregates after Middle Cerebral Artery Occlusion

BACKGROUND AND PURPOSE: Cerebral ischemia leads to accumulation of ubiquitinated protein aggregates. However, the factors triggering ubiquitination and their impact on the outcome of cerebral ischemia remain poorly understood. Here we investigate the relationship between ubiquitin aggregation and du...

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Autors principals: Hochrainer, Karin, Jackman, Katherine, Anrather, Josef, Iadecola, Costantino
Format: Artigo
Idioma:Inglês
Publicat: 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404229/
https://ncbi.nlm.nih.gov/pubmed/22700531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.112.650416
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