Cerebral ischemia induces the aggregation of proteins linked to neurodegenerative diseases

Protein aggregation critically affects cell viability in neurodegenerative diseases, but whether this also occurs in ischemic brain injury remains elusive. Prior studies report the post-ischemic aggregation of ubiquitin, small ubiquitin-related modifier (SUMO) and ribosomes, however whether other pr...

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Pubblicato in:Sci Rep
Autori principali: Kahl, Anja, Blanco, Ismary, Jackman, Katherine, Baskar, Juhi, Milaganur Mohan, Harihar, Rodney-Sandy, Reunet, Zhang, Sheng, Iadecola, Costantino, Hochrainer, Karin
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807442/
https://ncbi.nlm.nih.gov/pubmed/29426953
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-21063-z
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