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Repression of mammary stem/progenitor cells by p53 is mediated by notch and separable from apoptotic activity
Breast cancer is the most common tumor among women with inherited mutations in the p53 gene (Li-Fraumeni syndrome). The tumors represent the basal-like subtype which has been suggested to originate from mammary stem/progenitor cells. In mouse mammary epithelium, mammosphere-forming potential was inc...
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| Auteurs principaux: | , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3404152/ https://ncbi.nlm.nih.gov/pubmed/21280161 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/stem.552 |
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