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Oncogenic transformation of mammary epithelial cells by transforming growth factor beta independent of mammary stem cell regulation
BACKGROUND: Transforming growth factor beta (TGFβ) is transiently increased in the mammary gland during involution and by radiation. While TGFβ normally has a tumour suppressor role, prolonged exposure to TGFβ can induce an oncogenic epithelial to mesenchymal transition (EMT) program in permissive c...
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| Glavni autori: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BioMed Central
2013
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3733955/ https://ncbi.nlm.nih.gov/pubmed/23883065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1475-2867-13-74 |
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