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Adenovirus Delivered Short Hairpin RNA Targeting a Conserved Site in the 5′ Non-Translated Region Inhibits All Four Serotypes of Dengue Viruses

BACKGROUND: Dengue is a mosquito-borne viral disease caused by four closely related serotypes of Dengue viruses (DENVs). This disease whose symptoms range from mild fever to potentially fatal haemorrhagic fever and hypovolemic shock, threatens nearly half the global population. There is neither a pr...

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Detalhes bibliográficos
Main Authors: Korrapati, Anil Babu, Swaminathan, Gokul, Singh, Aarti, Khanna, Navin, Swaminathan, Sathyamangalam
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404111/
https://ncbi.nlm.nih.gov/pubmed/22848770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001735
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