A small molecule inhibitor of dengue virus type 2 protease inhibits the replication of all four dengue virus serotypes in cell culture

BACKGROUND: Dengue has emerged as the most significant of arboviral diseases in the 21st century. It is endemic to >100 tropical and sub-tropical countries around the world placing an estimated 3.6 billion people at risk. It is caused by four genetically similar but antigenically distinct, seroty...

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Publicat a:Virol J
Autors principals: Raut, Rajendra, Beesetti, Hemalatha, Tyagi, Poornima, Khanna, Ira, Jain, Swatantra K, Jeankumar, Variam U, Yogeeswari, Perumal, Sriram, Dharmarajan, Swaminathan, Sathyamangalam
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4327787/
https://ncbi.nlm.nih.gov/pubmed/25886260
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12985-015-0248-x
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