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Adenovirus Delivered Short Hairpin RNA Targeting a Conserved Site in the 5′ Non-Translated Region Inhibits All Four Serotypes of Dengue Viruses

BACKGROUND: Dengue is a mosquito-borne viral disease caused by four closely related serotypes of Dengue viruses (DENVs). This disease whose symptoms range from mild fever to potentially fatal haemorrhagic fever and hypovolemic shock, threatens nearly half the global population. There is neither a pr...

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Autors principals: Korrapati, Anil Babu, Swaminathan, Gokul, Singh, Aarti, Khanna, Navin, Swaminathan, Sathyamangalam
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404111/
https://ncbi.nlm.nih.gov/pubmed/22848770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001735
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