Adenovirus Delivered Short Hairpin RNA Targeting a Conserved Site in the 5′ Non-Translated Region Inhibits All Four Serotypes of Dengue Viruses

BACKGROUND: Dengue is a mosquito-borne viral disease caused by four closely related serotypes of Dengue viruses (DENVs). This disease whose symptoms range from mild fever to potentially fatal haemorrhagic fever and hypovolemic shock, threatens nearly half the global population. There is neither a pr...

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Main Authors: Korrapati, Anil Babu, Swaminathan, Gokul, Singh, Aarti, Khanna, Navin, Swaminathan, Sathyamangalam
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404111/
https://ncbi.nlm.nih.gov/pubmed/22848770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001735
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