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PGC-1α is Dispensable for Exercise-Induced Mitochondrial Biogenesis in Skeletal Muscle

Exercise confers numerous health benefits, many of which are thought to stem from exercise-induced mitochondrial biogenesis (EIMB) in skeletal muscle. The transcriptional coactivator PGC-1α, a potent regulator of metabolism in numerous tissues, is widely believed to be required for EIMB. We show her...

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Main Authors: Rowe, Glenn C., El-Khoury, Riyad, Patten, Ian S., Rustin, Pierre, Arany, Zolt
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3404101/
https://ncbi.nlm.nih.gov/pubmed/22848618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041817
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