Ribonucleotide reductase inhibition restores platinum-sensitivity in platinum-resistant ovarian cancer: a Gynecologic Oncology Group Study

BACKGROUND: The potent ribonucleotide reductase (RNR) inhibitor 3-aminopyridine-2-carboxyaldehyde-thiosemicarbazone (3-AP) was tested as a chemosensitizer for restored cisplatin-mediated cytotoxicity in platinum-resistant ovarian cancer. METHODS: Preclinical in vitro platinum-resistant ovarian cance...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Kunos, Charles, Radivoyevitch, Tomas, Abdul-Karim, Fadi W, Fanning, James, Abulafia, Ovadia, Bonebrake, Albert J, Usha, Lydia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403898/
https://ncbi.nlm.nih.gov/pubmed/22541066
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-10-79
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados