CD44 signaling via PI3K/AKT and MAPK/ERK pathways protects CLL cells from spontaneous and drug induced apoptosis through MCL-1

Survival of chronic lymphocytic leukemia (CLL) cells in vivo is supported by the tissue microenvironment, which includes components of the extracellular matrix. Interactions between tumor cells and the extracellular matrix are in part mediated by CD44, whose principle ligand in this respect is hyalu...

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Detaylı Bibliyografya
Asıl Yazarlar: Herishanu, Yair, Gibellini, Federica, Njuguna, Ndegwa, Hazan-Halevy, Inbal, Keyvanfar, Keyvan, Lee, Elinor, Wilson, Wyndham, Wiestner, Adrian
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2011
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403533/
https://ncbi.nlm.nih.gov/pubmed/21649540
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/10428194.2011.569962
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