Structural basis of interleukin-5 dimer recognition by its α receptor

Interleukin-5 (IL-5), a major hematopoietin, stimulates eosinophil proliferation, migration, and activation, which have been implicated in the pathogenesis of allergic inflammatory diseases, such as asthma. The specific IL-5 receptor (IL-5R) consists of the IL-5 receptor α subunit (IL-5RA) and the c...

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Main Authors: Kusano, Seisuke, Kukimoto-Niino, Mutsuko, Hino, Nobumasa, Ohsawa, Noboru, Ikutani, Masashi, Takaki, Satoshi, Sakamoto, Kensaku, Hara-Yokoyama, Miki, Shirouzu, Mikako, Takatsu, Kiyoshi, Yokoyama, Shigeyuki
Format: Artigo
Language:Inglês
Published: Wiley Subscription Services, Inc., A Wiley Company 2012
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403420/
https://ncbi.nlm.nih.gov/pubmed/22528658
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.2072
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