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High precision alignment of cryo-electron subtomograms through gradient-based parallel optimization

BACKGROUND: Cryo-electron tomography emerges as an important component for structural system biology. It not only allows the structural characterization of macromolecular complexes, but also the detection of their cellular localizations in near living conditions. However, the method is hampered by l...

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Detalhes bibliográficos
Main Authors: Xu, Min, Alber, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403359/
https://ncbi.nlm.nih.gov/pubmed/23046491
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1752-0509-6-S1-S18
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