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Automated target segmentation and real space fast alignment methods for high-throughput classification and averaging of crowded cryo-electron subtomograms

Motivation: Cryo-electron tomography allows the imaging of macromolecular complexes in near living conditions. To enhance the nominal resolution of a structure it is necessary to align and average individual subtomograms each containing identical complexes. However, if the sample of complexes is het...

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Detalhes bibliográficos
Main Authors: Xu, Min, Alber, Frank
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3694676/
https://ncbi.nlm.nih.gov/pubmed/23812994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btt225
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