Lung endothelial ADAM17 regulates the acute inflammatory response to lipopolysaccharide

Acute lung injury (ALI) is associated with increased vascular permeability, leukocyte recruitment, and pro-inflammatory mediator release. We investigated the role of the metalloproteinase ADAM17 in endotoxin-induced ALI with focus on endothelial ADAM17. In vitro, endotoxin-mediated induction of endo...

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Bibliografiska uppgifter
Huvudupphovsmän: Dreymueller, Daniela, Martin, Christian, Kogel, Tanja, Pruessmeyer, Jessica, Hess, Franz M, Horiuchi, Keisuke, Uhlig, Stefan, Ludwig, Andreas
Materialtyp: Artigo
Språk:Inglês
Publicerad: WILEY-VCH Verlag 2012
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403298/
https://ncbi.nlm.nih.gov/pubmed/22367719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200217
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