Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease

Induced pluripotent stem cells (iPSC) offer an unprecedented opportunity to model human disease in relevant cell types, but it is unclear whether they could successfully model age-related diseases such as Parkinson's disease (PD). Here, we generated iPSC lines from seven patients with idiopathi...

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Bibliografiska uppgifter
Huvudupphovsmän: Sánchez-Danés, Adriana, Richaud-Patin, Yvonne, Carballo-Carbajal, Iria, Jiménez-Delgado, Senda, Caig, Carles, Mora, Sergio, Di Guglielmo, Claudia, Ezquerra, Mario, Patel, Bindiben, Giralt, Albert, Canals, Josep M, Memo, Maurizio, Alberch, Jordi, López-Barneo, José, Vila, Miquel, Cuervo, Ana Maria, Tolosa, Eduard, Consiglio, Antonella, Raya, Angel
Materialtyp: Artigo
Språk:Inglês
Publicerad: WILEY-VCH Verlag 2012
Ämnen:
Research Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403296/
https://ncbi.nlm.nih.gov/pubmed/22407749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200215
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