Disease-specific phenotypes in dopamine neurons from human iPS-based models of genetic and sporadic Parkinson's disease

Induced pluripotent stem cells (iPSC) offer an unprecedented opportunity to model human disease in relevant cell types, but it is unclear whether they could successfully model age-related diseases such as Parkinson's disease (PD). Here, we generated iPSC lines from seven patients with idiopathi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Sánchez-Danés, Adriana, Richaud-Patin, Yvonne, Carballo-Carbajal, Iria, Jiménez-Delgado, Senda, Caig, Carles, Mora, Sergio, Di Guglielmo, Claudia, Ezquerra, Mario, Patel, Bindiben, Giralt, Albert, Canals, Josep M, Memo, Maurizio, Alberch, Jordi, López-Barneo, José, Vila, Miquel, Cuervo, Ana Maria, Tolosa, Eduard, Consiglio, Antonella, Raya, Angel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: WILEY-VCH Verlag 2012
Pynciau:
Research Articles
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3403296/
https://ncbi.nlm.nih.gov/pubmed/22407749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/emmm.201200215
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