Kv1.1 knock-in ataxic mice exhibit spontaneous myokymic activity exacerbated by fatigue, ischemia and low temperature

Episodic ataxia type 1 (EA1) is an autosomal dominant neurological disorder characterized by myokymia and attacks of ataxic gait often precipitated by stress. Several genetic mutations have been identified in the Shaker-like K(+) channel Kv1.1 (KCNA1) of EA1 individuals, including V408A, which resul...

Descrición completa

Gardado en:
Detalles Bibliográficos
Main Authors: Brunetti, Orazio, Imbrici, Paola, Botti, Fabio Massimo, Pettorossi, Vito Enrico, D'Adamo, Maria Cristina, Valentino, Mario, Zammit, Christian, Mora, Marina, Gibertini, Sara, Di Giovanni, Giuseppe, Muscat, Richard, Pessia, Mauro
Formato: Artigo
Idioma:Inglês
Publicado: Academic Press 2012
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402927/
https://ncbi.nlm.nih.gov/pubmed/22609489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2012.05.002
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares