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Pushing the envelope of retinal ganglion cell genesis: context dependent function of Math5 (Atoh7)
The basic-helix-loop helix factor Math5 (Atoh7) is required for retinal ganglion cell (RGC) development. However, only 10% of Math5-expressing cells adopt the RGC fate, and most become photoreceptors. In principle, Math5 may actively bias progenitors towards RGC fate or passively confer competence t...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3402631/ https://ncbi.nlm.nih.gov/pubmed/22609278 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.05.005 |
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