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Pushing the envelope of retinal ganglion cell genesis: context dependent function of Math5 (Atoh7)

The basic-helix-loop helix factor Math5 (Atoh7) is required for retinal ganglion cell (RGC) development. However, only 10% of Math5-expressing cells adopt the RGC fate, and most become photoreceptors. In principle, Math5 may actively bias progenitors towards RGC fate or passively confer competence t...

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Autors principals: Prasov, Lev, Glaser, Tom
Format: Artigo
Idioma:Inglês
Publicat: 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402631/
https://ncbi.nlm.nih.gov/pubmed/22609278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2012.05.005
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