Markers of Endogenous Desaturase Activity and Risk of Coronary Heart Disease in the CAREMA Cohort Study

BACKGROUND: Intakes of n-3 polyunsaturated fatty acids (PUFAs), especially EPA (C20∶5n-3) and DHA (C22∶6n-3), are known to prevent fatal coronary heart disease (CHD). The effects of n-6 PUFAs including arachidonic acid (C20∶4n-6), however, remain unclear. δ-5 and δ-6 desaturases are rate-limiting en...

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Autores principales: Lu, Yingchang, Vaarhorst, Anika, Merry, Audrey H. H., Dollé, Martijn E. T., Hovenier, Robert, Imholz, Sandra, Schouten, Leo J., Heijmans, Bastiaan T., Müller, Michael, Slagboom, P. Eline, van den Brandt, Piet A., Gorgels, Anton P. M., Boer, Jolanda M. A., Feskens, Edith J. M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402436/
https://ncbi.nlm.nih.gov/pubmed/22911844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041681
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