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Conformational Analysis of Clostridium difficile Toxin B and Its Implications for Substrate Recognition
Clostridium difficile (C. difficile) is an opportunistic pathogen that can cause potentially lethal hospital-acquired infections. The cellular damage that it causes is the result of two large clostridial cytotoxins: TcdA and TcdB which act by glucosylating cytosolic G-proteins, mis-regulation of whi...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3402401/ https://ncbi.nlm.nih.gov/pubmed/22844485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041518 |
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