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Conformational Analysis of Clostridium difficile Toxin B and Its Implications for Substrate Recognition

Clostridium difficile (C. difficile) is an opportunistic pathogen that can cause potentially lethal hospital-acquired infections. The cellular damage that it causes is the result of two large clostridial cytotoxins: TcdA and TcdB which act by glucosylating cytosolic G-proteins, mis-regulation of whi...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Swett, Rebecca, Cisneros, G. Andrés, Feig, Andrew L.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Public Library of Science 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402401/
https://ncbi.nlm.nih.gov/pubmed/22844485
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0041518
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