Maturation of Human Embryonic Stem Cell–Derived Pancreatic Progenitors Into Functional Islets Capable of Treating Pre-existing Diabetes in Mice

Diabetes is a chronic debilitating disease that results from insufficient production of insulin from pancreatic β-cells. Islet cell replacement can effectively treat diabetes but is currently severely limited by the reliance upon cadaveric donor tissue. We have developed a protocol to efficiently di...

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Autors principals: Rezania, Alireza, Bruin, Jennifer E., Riedel, Michael J., Mojibian, Majid, Asadi, Ali, Xu, Jean, Gauvin, Rebecca, Narayan, Kavitha, Karanu, Francis, O’Neil, John J., Ao, Ziliang, Warnock, Garth L., Kieffer, Timothy J.
Format: Artigo
Idioma:Inglês
Publicat: American Diabetes Association 2012
Matèries:
Islet Studies
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402300/
https://ncbi.nlm.nih.gov/pubmed/22740171
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1711
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