Production of Functional Glucagon-Secreting α-Cells From Human Embryonic Stem Cells

OBJECTIVE: Differentiation of human embryonic stem (hES) cells to fully developed cell types holds great therapeutic promise. Despite significant progress, the conversion of hES cells to stable, fully differentiated endocrine cells that exhibit physiologically regulated hormone secretion has not yet...

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Detalhes bibliográficos
Main Authors: Rezania, Alireza, Riedel, Michael J., Wideman, Rhonda D., Karanu, Francis, Ao, Ziliang, Warnock, Garth L., Kieffer, Timothy J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2011
Assuntos:
Immunology and Transplantation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3012176/
https://ncbi.nlm.nih.gov/pubmed/20971966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0573
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