Amyloid formation disrupts the balance between interleukin-1β and interleukin-1 receptor antagonist in human islets

OBJECTIVES: β-cell dysfunction and apoptosis associated with islet inflammation play a key role in the pathogenesis of type 2 diabetes (T2D). Growing evidence suggests that islet amyloid, formed by aggregation of human islet amyloid polypeptide (hIAPP), contributes to islet inflammation and β-cell d...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Mol Metab
Hoofdauteurs: Hui, Queenie, Asadi, Ali, Park, Yoo Jin, Kieffer, Timothy J., Ao, Ziliang, Warnock, Garth L., Marzban, Lucy
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Elsevier 2017
Onderwerpen:
Original Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5518725/
https://ncbi.nlm.nih.gov/pubmed/28752047
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2017.05.016
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items