Loss of the Endothelial Glycocalyx Links Albuminuria and Vascular Dysfunction

Patients with albuminuria and CKD frequently have vascular dysfunction but the underlying mechanisms remain unclear. Because the endothelial surface layer, a meshwork of surface-bound and loosely adherent glycosaminoglycans and proteoglycans, modulates vascular function, its loss could contribute to...

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Main Authors: Salmon, Andrew H.J., Ferguson, Joanne K., Burford, James L., Gevorgyan, Haykanush, Nakano, Daisuke, Harper, Steven J., Bates, David O., Peti-Peterdi, Janos
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Nephrology 2012
Fag:
Basic Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402289/
https://ncbi.nlm.nih.gov/pubmed/22797190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2012010017
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