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Pharmacologic reversal of epigenetic silencing of the anticancer protein BRM: a novel targeted treatment strategy
Tumor suppressor genes and oncogenes are both commonly altered during carcinogenesis. For oncogenes and other genes that drive growth, targeting mutated or activated forms (such as the EGFR-Her2/Nneu pathway) has been shown to be an effective anti-cancer approach. Pharmacologically targeting tumor s...
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| Hauptverfasser: | , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3402205/ https://ncbi.nlm.nih.gov/pubmed/21478905 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2011.80 |
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