Ribosome Assembly Factors Prevent Premature Translation Initiation by 40S Assembly Intermediates

Ribosome assembly in eukaryotes requires approximately 200 essential assembly factors (AFs), and occurs via ordered events that initiate in the nucleolus and culminate in the cytoplasm. Here we present the cryo-electron microscopy (cryo-EM) structure of a late cytoplasmic 40S ribosome assembly inter...

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Main Authors: Strunk, Bethany S., Loucks, Cherisse R., Su, Min, Vashisth, Harish, Cheng, Shanshan, Schilling, Justin, Brooks, Charles L., Karbstein, Katrin, Skiniotis, Georgios
Format: Artigo
Jezik:Inglês
Izdano: 2011
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402165/
https://ncbi.nlm.nih.gov/pubmed/21835981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1208245
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