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The case for therapeutic proteostasis modulators
A functional ubiquitin proteasome pathway (UPP) is vital for all eukaryotic cellular systems and therefore any alteration in this critical component of proteostasis machinery has rpotential pathological consequences. A proteostasis imbalance can be induced by environmental pollutants, age or genetic...
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| Auteur principal: | |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401941/ https://ncbi.nlm.nih.gov/pubmed/21250874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2011.553610 |
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