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Early-Age-Related Changes in Proteostasis Augment Immunopathogenesis of Sepsis and Acute Lung Injury

BACKGROUND: The decline of proteasomal activity is known to be associated with the age-related disorders but the early events involved in this process are not apparent. To address this, we investigated the early-age-related (pediatric vs. adult) mechanisms that augment immunopathogenesis of sepsis a...

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Detalhes bibliográficos
Main Authors: Bodas, Manish, Min, Taehong, Vij, Neeraj
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2981560/
https://ncbi.nlm.nih.gov/pubmed/21085581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0015480
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