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New Synthetic Methodology for the Construction of 7-Substituted Farnesyl Diphosphate Analogs
Through the use of a 1,2-metalate rearrangement, six 7-substituted farnesol analogs were generated in a concise manner. This new synthetic route allowed us to quickly prepare several diverse farnesyl diphosphate analogs with interesting biological activities against mammalian protein-farnesyl transf...
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| Main Authors: | , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2011
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401630/ https://ncbi.nlm.nih.gov/pubmed/21699139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol201069x |
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