Iron-overload decreases Cav1.3-dependent L-type Ca(2+) currents leading to bradycardia, altered electrical conduction and atrial fibrillation

BACKGROUND: Chronic iron-overload (CIO) is associated with blood disorders such as thalassemias and hemochromatosis. A major prognostic indicator of survival in patients with CIO is iron-mediated cardiomyopathy, characterized by contractile dysfunction and electrical disturbances including slow hear...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Rose, Robert A., Sellan, Michael, Simpson, Jeremy A., Izaddoustdar, Farzad, Cifelli, Carlo, Panama, Brian K., Davis, Mark, Zhao, Dongling, Markhani, Moniba, Murphy, Geoffrey G., Striessnig, Joerg, Liu, Peter P., Heximer, Scott P., Backx, Peter H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401539/
https://ncbi.nlm.nih.gov/pubmed/21747058
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCEP.110.960401
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados