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Bacterial biosynthesis and maturation of the didemnin anticancer agents

The antineoplastic agent didemnin B from the Caribbean tunicate Trididemnum solidum was the first marine drug to be clinically tested in humans. Because of its limited supply and its complex cyclic depsipeptide structure, considerable challenges were encountered during didemnin B's development...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Xu, Ying, Kersten, Roland D., Nam, Sang-Jip, Lu, Liang, Al-Suwailem, Abdulaziz M., Zheng, Huajun, Fenical, William, Dorrestein, Pieter C., Moore, Bradley S., Qian, Pei-Yuan
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401512/
https://ncbi.nlm.nih.gov/pubmed/22458477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja301735a
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