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let-7-Complex microRNAs regulate the temporal identity of Drosophila mushroom body neurons via chinmo

Many neural lineages display a temporal pattern, but the mechanisms controlling the ordered production of neuronal subtypes remains unclear. Here, we show that Drosophila let-7 and miR-125, co-transcribed from the let-7-Complex (let-7-C) locus, regulate the transcription factor chinmo to control tem...

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Bibliografski detalji
Glavni autori: Wu, Yen-Chi, Chen, Ching-Huan, Mercer, Adam, Sokol, Nicholas S.
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401410/
https://ncbi.nlm.nih.gov/pubmed/22814608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2012.05.013
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