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A let-7-to-miR-125 MicroRNA Switch Regulates Neuronal Integrity and Lifespan in Drosophila

Messenger RNAs (mRNAs) often contain binding sites for multiple, different microRNAs (miRNAs). However, the biological significance of this feature is unclear, since such co-targeting miRNAs could function coordinately, independently, or redundantly with one another. Here, we show that two co-transc...

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Vydáno v:PLoS Genet
Hlavní autoři: Chawla, Geetanjali, Deosthale, Padmini, Childress, Sue, Wu, Yen-chi, Sokol, Nicholas S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4979967/
https://ncbi.nlm.nih.gov/pubmed/27508495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006247
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