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Hormonal activation of let-7-C microRNAs via EcR is required for adult Drosophila melanogaster morphology and function
Steroid hormones and their nuclear receptors drive developmental transitions in diverse organisms, including mammals. In this study, we show that the Drosophila steroid hormone 20-hydroxyecdysone (20E) and its nuclear receptor directly activate transcription of the evolutionarily conserved let-7-com...
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| 主要な著者: | , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Company of Biologists
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3328179/ https://ncbi.nlm.nih.gov/pubmed/22510985 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.077743 |
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