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ATM-Dependent Downregulation of USP7/HAUSP by PPM1G Activates p53 Response to DNA Damage

The deubiquitylation enzyme USP7/HAUSP plays a major role in regulating genome stability and cancer prevention by controlling the key proteins involved in the DNA damage response. Despite this important role in controlling other proteins, USP7 itself has not been recognized as a target for regulatio...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Khoronenkova, Svetlana V., Dianova, Irina I., Ternette, Nicola, Kessler, Benedikt M., Parsons, Jason L., Dianov, Grigory L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Cell Press 2012
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401373/
https://ncbi.nlm.nih.gov/pubmed/22361354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.01.021
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