Transcription Factor Zinc finger and BTB Domain 1 (Zbtb1) Is Essential for Lymphocyte Development

Absent T lymphocytes were unexpectedly found in homozygotes of a transgenic mouse from an unrelated project. T cell development did not progress beyond double negative stage 1 thymocytes, resulting in a hypocellular, vestigial thymus. B cells were present, but NK cell number and B cell isotype switc...

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Autori principali: Punwani, Divya, Simon, Karen, Choi, Youngnim, Dutra, Amalia, Gonzalez-Espinosa, Diana, Pak, Evgenia, Naradikian, Martin, Song, Chang-Hwa, Zhang, Jenny, Bodine, David M., Puck, Jennifer M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3401355/
https://ncbi.nlm.nih.gov/pubmed/22753936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200623
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