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Transcription Factor Zinc finger and BTB Domain 1 (Zbtb1) Is Essential for Lymphocyte Development
Absent T lymphocytes were unexpectedly found in homozygotes of a transgenic mouse from an unrelated project. T cell development did not progress beyond double negative stage 1 thymocytes, resulting in a hypocellular, vestigial thymus. B cells were present, but NK cell number and B cell isotype switc...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401355/ https://ncbi.nlm.nih.gov/pubmed/22753936 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200623 |
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