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Antigen-driven Induction of Polyreactive IgM during Intracellular Bacterial Infection
Polyreactivity is well known as a property of natural IgM produced by B-1 cells. We demonstrate that polyreactive IgM is also generated during infection of mice with Ehrlichia muris, a tick-borne intracellular bacterial pathogen. The polyreactive IgM bound self and foreign antigens, including single...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401281/ https://ncbi.nlm.nih.gov/pubmed/22730531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200878 |
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