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Inhibition of Granzyme B by PI-9 protects prostate cancer cells from apoptosis
BACKGROUND: In order for tumors to grow and proliferate, they must avoid recognition by immune cells and subsequent death by apoptosis. Granzyme B, a protease located in natural killer cells, initiates apoptosis in target cells. Inhibition of Granzyme B by PI-9, its natural inhibitor, can prevent ap...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3401211/ https://ncbi.nlm.nih.gov/pubmed/21919028 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.21486 |
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