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Toxoplasma gondii inhibits granzyme B-mediated apoptosis by the inhibition of granzyme B function in host cells

Host defense to the apicomplexan parasite Toxoplasma gondii is critically dependent on CD8(+) T cells, whose effector functions include the induction of apoptosis in target cells following the secretion of granzyme proteases. Here we demonstrate that T. gondii induces resistance of host cells to apo...

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Detalhes bibliográficos
Main Authors: Yamada, Tatsuya, Tomita, Tadakimi, Weiss, Louis M., Orlofsky, Amos
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3116727/
https://ncbi.nlm.nih.gov/pubmed/21329693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ijpara.2010.11.012
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