Llwytho...

Intracellular parasitism with Toxoplasma gondii stimulates mTOR-dependent host cell growth despite impaired signaling to S6K1 and 4E-BP1

The Ser/Thr kinase mTOR is a central regulator of anabolism, growth and proliferation. We investigated the effects of Toxoplasma gondii on host mTOR signaling. Toxoplasma invasion of multiple cell types rapidly induced sustained mTOR activation that was restricted to infected cells, as determined by...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Wang, Yubao, Weiss, Louis M., Orlofsky, Amos
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880858/
https://ncbi.nlm.nih.gov/pubmed/19302577
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1462-5822.2009.01305.x
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