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Mechanisms of SecM-Mediated Stalling in the Ribosome

Nascent-peptide modulation of translation is a common regulatory mechanism of gene expression. In this mechanism, while the nascent peptide is still in the exit tunnel of the ribosome, it induces translational pausing, thereby controlling the expression of downstream genes. One example is SecM, whic...

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Détails bibliographiques
Auteurs principaux: Gumbart, James, Schreiner, Eduard, Wilson, Daniel N., Beckmann, Roland, Schulten, Klaus
Format: Artigo
Langue:Inglês
Publié: The Biophysical Society 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400775/
https://ncbi.nlm.nih.gov/pubmed/22853911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.06.005
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