Mechanisms of SecM-Mediated Stalling in the Ribosome

Nascent-peptide modulation of translation is a common regulatory mechanism of gene expression. In this mechanism, while the nascent peptide is still in the exit tunnel of the ribosome, it induces translational pausing, thereby controlling the expression of downstream genes. One example is SecM, whic...

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Bibliographic Details
Main Authors: Gumbart, James, Schreiner, Eduard, Wilson, Daniel N., Beckmann, Roland, Schulten, Klaus
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2012
Subjects:
Proteins and Nucleic Acids
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400775/
https://ncbi.nlm.nih.gov/pubmed/22853911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.06.005
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