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Mechanisms of SecM-Mediated Stalling in the Ribosome

Nascent-peptide modulation of translation is a common regulatory mechanism of gene expression. In this mechanism, while the nascent peptide is still in the exit tunnel of the ribosome, it induces translational pausing, thereby controlling the expression of downstream genes. One example is SecM, whic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Gumbart, James, Schreiner, Eduard, Wilson, Daniel N., Beckmann, Roland, Schulten, Klaus
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3400775/
https://ncbi.nlm.nih.gov/pubmed/22853911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.06.005
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